Curing GERD with Pariet
Pariet, the brand name for rabeprazole sodium, is a proton pump inhibitor which acts by suppressing gastric acid secretion by blocking acid (proton) pump within gastric parietal cells. Pariet is extensively metabolized in liver by CYP3A to sulfone metabolite and CYP2C19 to desmethyl rabeprazole. Thioether metabolite is formed by reduction of rabeprazole and these metabolites do not have any important anti secretory activity.
The benefits of Pariet are as follows:
It is a short-term treatment in healing and symptomatic relief of duodenal ulcers and erosive or ulcerative gastroesophageal reflux disease.
It maintains the healing and reducing relapse rates
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